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Report of Three Cases

Dorothy Nicholson, MD; Steven White, MD; Ace Lipson, MD; Robert P. Jacobs, MD; David G. Borenstein, MD

Arch Intern Med. 1986;146(12):2350-2352.

Abstract
• Progressive systemic sclerosis (PSS) is associated with a broad spectrum of autoimmune thyroid diseases. While an association between PSS and hypothyroidism is well established, a relationship between PSS and hyperthyroidism is less well defined. We treated three patients with PSS whose course was complicated by Graves' disease. Because hyperthyroidism can simulate many of the symptoms of PSS progression and treatment of hyperthyroidism can lead to resolution of clinical deterioration in such patients, it is important to recognize the simultaneous occurrence of these diseases.

(Arch Intern Med 1986;146:2350-2352)

Author Affiliations
From the Department of Medicine (Dr White), the Divisions of Rheumatology (Drs Nicholson and Borenstein) and Endocrinology (Dr Lipson), The George Washington University Medical Center, Washington, DC; and the Department of Medicine (Dr Jacobs), Jeanes Hospital, Philadelphia.

Footnotes
Accepted for publication March 21,1986.

Reprint requests to Division of Rheumatology, George Washington University Medical Center, 2150 Pennsylvania Ave NW, Washington, DC 20037 (Dr Borenstein).

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