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Herbal Medicine for the Treatment of Cardiovascular Disease
Clinical Considerations
Nick H. Mashour, MD;
George I. Lin, MD;
William H. Frishman, MD
Arch Intern Med. 1998;158:2225-2234.
Herbs have been used as medical treatments since the beginning of civilization and some derivatives (eg, aspirin, reserpine, and digitalis) have become mainstays of human pharmacotherapy. For cardiovascular diseases, herbal treatments have been used in patients with congestive heart failure, systolic hypertension, angina pectoris, atherosclerosis, cerebral insufficiency, venous insufficiency, and arrhythmia. However, many herbal remedies used today have not undergone careful scientific assessment, and some have the potential to cause serious toxic effects and major drug-to-drug interactions. With the high prevalence of herbal use in the United States today, clinicians must inquire about such health practices for cardiac disease and be informed about the potential for benefit and harm. Continuing research is necessary to elucidate the pharmacological activities of the many herbal remedies now being used to treat cardiovascular diseases.
From the Department of Medicine, The Albert Einstein College of Medicine, Bronx, NY (Dr Mashour); the Department of Family Medicine, Columbia Presbyterian Medical Center, New York, NY (Dr Lin); and the Departments of Medicine and Pharmacology, New York Medical College/Westchester Medical Center, Valhalla, NY (Dr Frishman).
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