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I am writing on behalf of the National Mental Health Association (NMHA) in response to the article titled "Off-label Prescribing Among Office-Based Physicians" by Radley et al.¹

As an organization, NMHA is concerned with the inappropriate prescribing of medications; however, we are also concerned about the potential to conclude from the study by Radley et al,¹ that all off-label prescribing is inappropriate. The study's conclusion that off-label use of medications lacks rigorous scientific scrutiny has strong implications and could lead to a false assumption about the usefulness of off-label prescribing.

While there is a dearth of scientific research on off-label prescribing, off-label treatments can be grounded in top-notch research and have proved to be beneficial for many individuals. At NMHA, we believe that this study does not highlight the positive outcomes that can result from off-label prescribing practices. Through the appropriate use of off-label prescriptions, physicians can successfully determine the . . . [Full Text of this Article]

AUTHOR INFORMATION
Jennifer L. Bright, MPA

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RELATED LETTER

Positive Outcomes Through the Appropriate Use of Off-Label Prescribing—Reply
Randall S. Stafford, David C. Radley, and Stan N. Finkelstein
Arch Intern Med. 2006;166(22):2555.
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