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Jackson T. Wright Jr, MD, PhD; Jeffrey L. Probstfield, MD; William C. Cushman, MD; Sara Pressel, MS; Jeffrey A. Cutler, MD, MPH; Barry R. Davis, MD, PhD; Paula T. Einhorn, MD, MS; Mahboob Rahman, MD; Paul K. Whelton, MD, MSc; Charles E. Ford, PhD; L. Julian Haywood, MD; Karen L. Margolis, MD, MPH; Suzanne Oparil, MD; Henry R. Black, MD; Michael H. Alderman, MD; for the ALLHAT Collaborative Research Group

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We appreciate the favorable comments by Dr Onuigbo on this latest ALLHAT publication.¹ We were also impressed by the very positive findings in thiazide-treated patients. ALLHAT was designed to determine whether -blockers, ACEIs, or CCBs were superior to thiazide-type diuretics (prescribed at an appropriate dosage) as initial therapy for reduction of cardiovascular or renal outcomes.¹ While potentially understated, we believe that our overall conclusion that the thiazide-type diuretic was not surpassed is consistent with the data and trial . . . [Full Text of this Article]

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RELATED ARTICLE

ALLHAT Findings Revisited in the Context of Subsequent Analyses, Other Trials, and Meta-analyses
Jackson T. Wright, Jr, Jeffrey L. Probstfield, William C. Cushman, Sara L. Pressel, Jeffrey A. Cutler, Barry R. Davis, Paula T. Einhorn, Mahboob Rahman, Paul K. Whelton, Charles E. Ford, L. Julian Haywood, Karen L. Margolis, Suzanne Oparil, Henry R. Black, Michael H. Alderman, and for the ALLHAT Collaborative Research Group
Arch Intern Med. 2009;169(9):832-842.
ABSTRACT | FULL TEXT  

RELATED LETTER

ALLHAT Findings Revisited in the Context of Subsequent Analyses, Other Trials, and Meta-analyses
Macaulay A. C. Onuigbo
Arch Intern Med. 2009;169(19):1810.
EXTRACT | FULL TEXT